Error message

  • Notice: Undefined index: renseignementsParticipant in Drupal\members\Plugin\Helpers\MembersHelper->findAttribute() (line 26 of modules/members/src/Plugin/Helpers/MembersHelper.php).
    Drupal\members\Plugin\Helpers\MembersHelper->findAttribute(Array, 112) (Line: 232)
    Drupal\projects\Plugin\Helpers\ProjectsHelper->defineMembersAttributes(Array, Array) (Line: 43)
    Drupal\projects\Plugin\Helpers\ProjectsHelper->defineProjectTeam(Array) (Line: 416)
    Drupal\projects\Controller\ProjectsModuleController->addProjectsCompleteDetails(Array) (Line: 374)
    Drupal\projects\Controller\ProjectsModuleController->findAProject('PERSPEC', 1, Array) (Line: 197)
    Drupal\projects\Controller\ProjectsModuleController->projectsDetails('PERSPEC')
    call_user_func_array(Array, Array) (Line: 123)
    Drupal\Core\EventSubscriber\EarlyRenderingControllerWrapperSubscriber->Drupal\Core\EventSubscriber\{closure}() (Line: 573)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 124)
    Drupal\Core\EventSubscriber\EarlyRenderingControllerWrapperSubscriber->wrapControllerExecutionInRenderContext(Array, Array) (Line: 97)
    Drupal\Core\EventSubscriber\EarlyRenderingControllerWrapperSubscriber->Drupal\Core\EventSubscriber\{closure}() (Line: 151)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 68)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 191)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 128)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 82)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 52)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 694)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    
  • Warning: Invalid argument supplied for foreach() in Drupal\members\Plugin\Helpers\MembersHelper->findAttribute() (line 26 of modules/members/src/Plugin/Helpers/MembersHelper.php).
    Drupal\members\Plugin\Helpers\MembersHelper->findAttribute(Array, 112) (Line: 232)
    Drupal\projects\Plugin\Helpers\ProjectsHelper->defineMembersAttributes(Array, Array) (Line: 43)
    Drupal\projects\Plugin\Helpers\ProjectsHelper->defineProjectTeam(Array) (Line: 416)
    Drupal\projects\Controller\ProjectsModuleController->addProjectsCompleteDetails(Array) (Line: 374)
    Drupal\projects\Controller\ProjectsModuleController->findAProject('PERSPEC', 1, Array) (Line: 197)
    Drupal\projects\Controller\ProjectsModuleController->projectsDetails('PERSPEC')
    call_user_func_array(Array, Array) (Line: 123)
    Drupal\Core\EventSubscriber\EarlyRenderingControllerWrapperSubscriber->Drupal\Core\EventSubscriber\{closure}() (Line: 573)
    Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 124)
    Drupal\Core\EventSubscriber\EarlyRenderingControllerWrapperSubscriber->wrapControllerExecutionInRenderContext(Array, Array) (Line: 97)
    Drupal\Core\EventSubscriber\EarlyRenderingControllerWrapperSubscriber->Drupal\Core\EventSubscriber\{closure}() (Line: 151)
    Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 68)
    Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
    Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 191)
    Drupal\page_cache\StackMiddleware\PageCache->fetch(Object, 1, 1) (Line: 128)
    Drupal\page_cache\StackMiddleware\PageCache->lookup(Object, 1, 1) (Line: 82)
    Drupal\page_cache\StackMiddleware\PageCache->handle(Object, 1, 1) (Line: 47)
    Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 52)
    Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
    Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 694)
    Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
    

Perspective

  • Biological and genetic characteristics
Perspective

The results of this project will build the foundation for the implementation of a mammography screening approach based on individual risk rather than on age alone. This personalized approach will contribute to a better balance between the benefits and harms of breast cancer screening.

See the website

Project summary

The PERSPECTIVE project aims to evaluate a new mammography screening strategy that takes into account each woman’s individual risk of breast cancer. Using an innovative tool that combines genetic information with information on different risk factors, it will be possible to assess and determine the risk category of each woman. A screening action plan adapted to each risk category will then be proposed to the participants.

For this purpose, 5,000 Quebec women between the ages of 40 and 69 will be recruited. Participants simply have to fill out a questionnaire that will allow the collection of information related to a number of risk factors for breast cancer. Their mammogram will provide breast density measures while genetic markers will be analyzed from their saliva sample. After the results are returned to participants, they will then be asked to complete two follow-up questionnaires.

The PERSPECTIVE study is a large-scale research project involving more than 20 researchers from Quebec, Canada as well as internationally. The principal investigators of PERSPECTIVE are Jacques Simard, Full Professor at the Department of Molecular Medicine of the Faculty of Medicine at Université Laval, and Anna Maria Chiarelli, Professor at the Dalla Lana School of Public Health at the University of Toronto.

Project team

Jacques Simard, Project Leader
Jacques Simard

Project Leader

Faculty of Medicine

Université Laval

Anna Maria Chiarelli, Co-Project Leader
Anna Maria Chiarelli

Co-Project Leader

Dalla Lana School of Public Health

University of Toronto

Bartha Maria Knoppers, Co-Investigator
Bartha Maria Knoppers

Co-Investigator

Faculty of Medicine

McGill University

Hermann Nabi, Co-Investigator
Hermann Nabi

Co-Investigator

Faculty of Medicine

Université Laval

Jocelyne Chiquette, Co-Investigator
Jocelyne Chiquette

Co-Investigator

Faculty of Medicine

Université Laval

Laurence Eloy, Co-Investigator
Laurence Eloy

Co-Investigator

Programme québécois de cancérologie

Ministère de la Santé et des Services sociaux

Michel Dorval, Co-Investigator
Michel Dorval

Co-Investigator

Faculty of Pharmacy

Université Laval

Yann Joly, Co-Investigator
Yann Joly

Co-Investigator

Faculty of Medicine

McGill University

Jean-Sébastien Paquette, Collaborator
Jean-Sébastien Paquette

Collaborator

Faculty of Medicine

Université Laval

Marie-Hélène Guertin, Collaborator
Marie-Hélène Guertin

Collaborator

Institut national de santé publique du Québec

Philippe Després, Collaborator
Philippe Després

Collaborator

Faculty of Science and Engineering

Université Laval

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